解放军医学院学报Issue(2)：107-109,3.DOI:10.3969/j.issn.2095-5227.2013.02.003
耐亚胺培南鲍曼不动杆菌苯唑西林基因型分析
OXA genotypes of imipenem-resistant Acinetobacter baumannii
雷红 1董梅 1刘敏 1孙敏霞 1孟祥红 1佟爱华 1刘昕1
作者信息
- 1. 解放军第309医院 检验科，北京 100091
- 折叠
摘要
Abstract
Objective To provide the scientific evidence for the control of hospital infection with imipenem-resistant Acinetobacter baumannii and its epidemiological survey by investigating the prevalence of its OXA genotypes in our hospital. Methods The OXA genetypes of 68 imipenem-resistant Acinetobacter baumannii strains isolated in our hospital from April 2010 to December 2010 were analyzed by multiplex PCR. Results Of the 68 isolated imipenem-resistant Acinetobacter baumannii strains, 7 were OXA-51 positive gene with a detection rate of 10.29%, 60 were OXA-51 and OXA-23 positive gene with a detection rate of 88.24%, and 1 was OXA-51 and OXA-58 positive gene with a detection rate of 1.47%. No OXA-24 gene was detected. Conclusion OXA-51+OXA-23 genotype is the popular OXA genetype of imipenem-resistant Acinetobacter baumannii in our hospital, indicating that it is the most important mechanism underlying the resistance of imipenem-resistant Acinetobacter baumannii to carbapenemases in our hospital, and laboratory should strengthen its monitoring of enzyme-producing strains.关键词
鲍曼不动杆菌/OXA基因/多重PCRKey words
acinetobacter baumannii/OXA genes/multiplex PCR分类
医药卫生引用本文复制引用
雷红,董梅,刘敏,孙敏霞,孟祥红,佟爱华,刘昕..耐亚胺培南鲍曼不动杆菌苯唑西林基因型分析[J].解放军医学院学报,2013,(2):107-109,3.
