解放军医学院学报Issue(8)：848-850,3.DOI:10.3969/j.issn.2095-5227.2013.08.019
唾液腺动态显像定量分析在诊断原发干燥综合征中的应用价值
Application of quantitative dynamic salivary gland images in diagnosis of primary Sjogren syndrome
向阳 1宋丽萍1
作者信息
- 1. 辽宁医学院附属第一医院 核医学科，辽宁锦州 121000
- 折叠
摘要
Abstract
Objective To study the application of quantitative 99mTcO4-dynamic salivary gland images in diagnosis of primary Sjogren syndrome (pSS). Methods Forty-four pSS patients served as a pSS group and 28 healthy subjects served as a control group in this study. Their 99mTcO4-dynamic salivary gland images were observed. Time-activity curve (TAC) of gland and its function parameters, including uptake ratio (UR), relative uptake ratio (S/T), gland secretion rate (SR) and mean secretion velocity (SV) after acid stimulation, were collected from the drawing region of interest (ROI). Difference in each function parameter was analyzed between pSS group and control group. The accuracy of quantitative 99mTcO4-dynamic salivary gland images was assessed according to the ROC curve. Results The gland UR and S/T were significantly lower, the gland SR after acid stimulation was significantly lower, the gland SV after acid stimulation was significantly slower in pSS group than in control group (P < 0.01). ROC curve showed that the sensitivity of gland SV and the specificity of gland UR were the highest in diagnosis of pSS among the parameters. Conclusion Quan-titative 99mTcO4-dynamic salivary gland images can be used in diagnosis of pSS with a high sensitivity and specificity, thus playing an important role in assessment of the uptake and secretion function of salivary gland.关键词
原发干燥综合征/唾液腺动态显像/定量分析Key words
primary Sjogren's syndrome/dynamic salivary gland images/quantitative analysis分类
医药卫生引用本文复制引用
向阳,宋丽萍..唾液腺动态显像定量分析在诊断原发干燥综合征中的应用价值[J].解放军医学院学报,2013,(8):848-850,3.
