检验医学与临床Issue(16)：2092-2093,2095,3.DOI:10.3969/j.issn.1672-9455.2013.16.014
血清肌酐两种测定方法偏倚的比较
Comparson the bias of two methods in detecting serum creatinine
程开书 1孙建民 1方兰1
作者信息
- 1. 安徽淮南矿业集团职业病防治院检验科 232003
- 折叠
摘要
Abstract
Objective To analyze the bias between sarcosine oxidase and Jaffe's methods for measuring the ser-um creatinine (Cre) .Methods According to the procedure described by the NCCLS approved guideline ,40 patients samples were analyzed in 5 operating days ,each sample was analyzed in duplicate by both enzymatic assay and Jaffe's kinetic assay .The duplicates were assessed for each method within the same run .The coefficient of correlation was calculated and the bias between two methods was calculated accordingly .Results The bias between the enzymatic as-say and Jaffe's kinetic assay were 1 .5% at 100 μmol/L ,6 .4% at 300 μmol/L and 7 .9% at 500 μmol/L for creati-nine .Conclusion The bias between two methods could be increased as the concentration of the serum creatinine in-creases .New reference range for creatinine should be established when new instrument or new reagent is applied .关键词
肌酐/肌氨酸氧化酶法/苦味酸法/比较Key words
creatinine/sarcosine oxidase/Jaffe's methods/comparison引用本文复制引用
程开书,孙建民,方兰..血清肌酐两种测定方法偏倚的比较[J].检验医学与临床,2013,(16):2092-2093,2095,3.
