检验医学与临床Issue(21)：3167-3168,3171,3.DOI:10.3969/j.issn.1672-9455.2015.21.014
近红外光谱法快速检测肾上腺色腙片品质的应用研究
Study on application of rapid detection for quality of Carbazochrome Tablets by near infrared spectroscopy
摘要
Abstract
Objective To establish the brand discrimination model of near infrared technology for Carbazo‐chrome Tablets in order to attack the counterfeit products .Methods In the module of Opus Setup Conformity Test , the model‐building parameters :the waveband was at the 9 000-7 500 ,6 900 -5 600 and 5 000 -4 250/cm ,the CI value was 7 ,the smooth point was 13 ,the pre‐processing method was second derivative plus vector normalization .The near infrared consistency model was established after the data pretreatment through the above parameters .Results 12 pieces of spectrum for verifying Carbazochrome Tablets from Jiangsu Yabang Apusen Pharmaceutical Co .,Ltd . were all within the limitation range of CI value 7 ,while the spectrum of 2 batches of counterfeit product exceeded the CI limit .Conclusion The brand model established by this method can rapidly identify the authenticity of this brand of drug ,and can be used for the preliminary screening of drugs in the daily surveillance work in order to increase the sampling hit rate .关键词
近红外光谱法/定性模型/肾上腺色腙片Key words
near infrared spectroscopy/qualitative model/Carbazochrome Tablets引用本文复制引用
李明梅,裘兰兰,王梅娟..近红外光谱法快速检测肾上腺色腙片品质的应用研究[J].检验医学与临床,2015,(21):3167-3168,3171,3.基金项目
江苏省盐城市医学科技发展计划项目（YK2014059）。 （）
