检验医学与临床Issue(21)：3172-3174,3.DOI:10.3969/j.issn.1672-9455.2015.21.016
肥胖型和非肥胖型多囊卵巢综合征患者的内分泌特征比较
Comparison of endocrine characteristics between obese and non-obese women with polycystic ovary syndrome
摘要
Abstract
Objective To investigate whether having the same endocrine characteristics in non‐obese and obese women with polycystic ovary syndrome (PCOS) .Methods 211 untreated women with PCOS were selected and divid‐ed into the obese group and the non‐obese group .The basal levels of serum total testosterone(TT) ,dehydroepiandro‐sterone sulfate (DHEAS ) ,sex hormone binding globulin (SHBG ) ,follicle stimulating hormone (FSH ) ,luteinizing hormone(LH) ,estradiol (E2) ,progesterone (PO) and prolactin(PRL) were measured and the results were analyzed statistically .Results The basal SHBG ,LH ,E2 and PO levels in the PCOS patients of the obese group were signifi‐cantly lower than those of the non‐obese group ,the difference was statistically significant (P<0 .05) .Obese was ab‐solutely positively correlated with the TT ,FSH and E2 levels in the PCOS patients ,but absolutely inversely correla‐ted with the SHBG ,LH and PO levels(P<0 .05) .Conclusion The difference of basal endocrine indicators exist be‐tween non‐obese and obese women with PCOS ,which has an important significance for further understanding the pathogenesis and heterogeneity of PCOS .关键词
多囊卵巢综合征/肥胖/内分泌指标/异质性Key words
PCOS/obese/endocrine indicators/heterogeneity引用本文复制引用
战思恩,王娟,翟燕红,王文娟..肥胖型和非肥胖型多囊卵巢综合征患者的内分泌特征比较[J].检验医学与临床,2015,(21):3172-3174,3.基金项目
首都医科大学附属北京妇产医院院内课题（2013-13）。 （）
