检验医学与临床Issue(21)：3204-3206,3.DOI:10.3969/j.issn.1672-9455.2015.21.028
慢性心力衰竭患者血清氨基末端脑钠肽前体及肌钙蛋白T 的检测意义
Significance of detection of serum NT-proBNP and cTnT in patients with chronic heart failure
摘要
Abstract
Objective To observe and analyze the changes and significance of serum N‐terminal pro‐brain nati‐uretic peptide (NT‐proBNP) and cardiac troponin T (cTnT ) in the patients with chronic heart failure (CHF) .Meth‐ods 100 cases of CHF were selected as the case group and 100 healthy persons were selected as the healthy control group .The serum NT‐proBNP and cTnT levels in the two group were detected and compared .Results The serum NT‐proBNP and cTnT levels in the case group were significantly higher than those in the healthy control group (t=22 .154 ,4 .817 ,P< 0 .05);with the increase of the cardiac function grade ,the serum NT‐proBNP and cTnT levels showed a gradually upward trend and the differences of the indexes among the different cardiac function grades were statistically significant (q=3 .463-26 .384 ,P<0 .05);the above two indexes were positively correlated with the car‐diac function grade(rs =0 .756 ,0 .433 ,P<0 .05) .Conclusion The significant increase of serum NT‐proBNP and cT‐nT levels in the patients with CHF reflect the injury of myocardial cells and the damage of cardiac function ,which are correlated with the cardiac function grade and can be used as the auxiliary indexes for evaluating the heart function status of the patients and the severity of the diseases .关键词
慢性心力衰竭/氨基末端脑钠肽前体/心肌肌钙蛋白T/心功能分级Key words
chronic heart failure/N-terminal pro-brain natiuretic peptide/cardiac troponin T/cardiac function classification引用本文复制引用
何蓉,李俊峰,薛成..慢性心力衰竭患者血清氨基末端脑钠肽前体及肌钙蛋白T 的检测意义[J].检验医学与临床,2015,(21):3204-3206,3.
