检验医学与临床Issue(22)：3371-3372,3375,3.DOI:10.3969/j.issn.1672-9455.2015.22.030
凝血四项及 AT-Ⅲ、D-二聚体在肝硬化患者中的变化及临床意义
Changes of 4 coagulation indicators and AT-Ⅲ,D-dimer in patients with liver cirrhosis and their clinical significance
杨倩1
作者信息
- 1. 陕西中医药大学附属医院检验科，西安 712000
- 折叠
摘要
Abstract
Objective To observe the expressions of plasma 4 coagulation indicators ,AT‐Ⅲ and D‐dimer(DD) in the patients with clinical liver cirrhosis and to investigate their clinical significance .Methods 80 patients with liver cirrhosis were selected as the observation subjects(group A) ,including 21 cases of stage A ,37 cases of stage B and 22 cases of stage C ;contemporaneous 80 volunteers undergoing the healthy physical examination were taken as the ob‐servation subjects(group B) and 80 cases of chronic hepatitis B as the observation subjects(group C) .The 4 coagula‐tion indicators ,AT‐Ⅲ and DD levels were detected and the detection results were performed the contrastive analysis . Results The APTT ,PT ,TT and D‐D levels in the group A and C were significantly higher than those in the group B ,moreover the FIB and AT‐Ⅲ levels were significantly lower than those in the group B ,the differences were statis‐tically significant(P<0 .05);the 4 coagulation indicators ,AT‐Ⅲ and D‐D levels were different among different liver function grade groups ,moreover the APTT ,PT ,TT and D‐D levels showed a gradual upward trend ,while the FIB and AT‐Ⅲ levels were decreased gradually .Conclusion The detection of 4 coagulation indicators ,AT‐Ⅲ and D‐D can more objectively reflect the coagulation status in the patients with liver cirrhosis ,which is convenient for doctors accurately assessing the severity of liver damage and provides a favorable basis for the late treatment of the patients .关键词
肝硬化/凝血四项/AT-Ⅲ/D-二聚体Key words
liver cirrhosis/4 coagulation indicators/AT-Ⅲ/D-dimer引用本文复制引用
杨倩..凝血四项及 AT-Ⅲ、D-二聚体在肝硬化患者中的变化及临床意义[J].检验医学与临床,2015,(22):3371-3372,3375,3.
