检验医学与临床Issue(23)：3505-3506,3509,3.DOI:10.3969/j.issn.1672-9455.2015.23.022
黛力新联合氟西汀治疗68例老年脑卒中后抑郁患者临床分析
Clinical analysis of deanxit combined with floxitine in 68 elder patients with post stroke depression
秦捷1
作者信息
- 1. 江苏省扬州市五台山医院精神一科 225003
- 折叠
摘要
Abstract
Objective To discuss the clinical effects and safety of combination of deanxit and floxitine in the treatment of elder patients with post stroke depression (PSD) .Methods From March 2010 to July 2013 ,68 PSD pa‐tients were collected in Yangzhou Wutaishan Hospital and divided into control group (n= 34) and observation group (n= 34) .Patients of control group were treated by floxitine ,and patients of observation group were treated by deanx‐it combined with floxitine .The scores of activity of daily living (ADL ) and Hamilton depression rating scale (HAMD) of two groups were compared before the treatment and 1 ,4 and 12 weeks after the treatment ,respectively . The clinical effects and complications of two groups were also compared .Results Before the treatment ,HAMD and ADL scores of two groups had no significant differences (P > 0 .05) .Compared with before the treatment ,HAMD and ADL scores of two groups all significantly decreased 1 ,4 and 12 weeks after the treatment (P < 0 .05) .HAMD and ADL scores of observation group were significantly lower than control group at every time point (P< 0 .05) .The effective rate of control group [73 .5% (25/34)] was significantly lower than observation group [47 .1% (16/34)] , with statistical difference (χ2 = 4 .096 ,P < 0 .05) .There was no significant difference of complication incidence be‐tween two groups (χ2 = 0 .078 ,P> 0 .05) .Conclusion Compared with fluorine treatment ,combination of deanxit and floxitine can significantly improve the depressive state of PSD elder patients and patients′self‐care abilities ,which is safe and effective ,and worthy of clinical application .关键词
脑卒中后抑郁/黛力新/氟西汀Key words
post stroke depression/deanxit/floxitine引用本文复制引用
秦捷..黛力新联合氟西汀治疗68例老年脑卒中后抑郁患者临床分析[J].检验医学与临床,2015,(23):3505-3506,3509,3.
