临床小儿外科杂志Issue(5)：357-360,4.DOI:10.3969/j.issn.1671-6353.2015.05.002
腹腔镜联合术中冰冻肝活检对胆道闭锁的诊断价值分析
Analysis on diagnosis of Laparoscopic combined intraoperative frozen liver biopsy in patients with bili-ary atresia
摘要
Abstract
Objetive To investigate the clinical application value of laparoscopic cholangiogram explora-tion combined intraoperative liver biopsy in diagnosis and treatment of infants with obstructive jaundice.Meth-ods In laparoscopic cholangiogram exploration,a small amount of liver tissue was sheared,then the quick fro-zen biopsy was got to assist the diagnosis,and the result was compared with postoperative pathology of paraffin section.Results 57 children with obstructive jaundice treated in our hospital between September 2012 and December 2013 underwent laparoscopic exploration,biliary cholangiography and intraoperative liver biopsy,55 cases were diagnosed as biliary atresia,and 2 cases cholestasis.According to the contrast of the intraoperative frozen section and postoperative paraffin section,both the degree of liver fibrosis and bile duct hyperplasia judg-ment is highly consistent(Kappa =0.675、0.871 、0.775),but inflammation in the hepatic lobule and portal ar-ea of frozen section is poorer(Kappa =0.309),the difference is statistically significant.Conclusions Intrao-perative liver biopsy combined laparoscopic exploration,biliary cholangiography is highly coincident with post-operative pathology,which can help get accurate judgment of the liver fibrosis degree and small bile duct hyper-plasia,and get diagnosis and pre -evaluation.关键词
腹腔镜/活组织检查/胆道闭锁/诊断Key words
Laparoscopes/Biopsy/Biliary atresia/Diagnosis引用本文复制引用
刘智文,杨文萍,黄金狮,陶强,陈快,陶俊峰,樊纬..腹腔镜联合术中冰冻肝活检对胆道闭锁的诊断价值分析[J].临床小儿外科杂志,2015,(5):357-360,4.基金项目
江西省卫计委科技计划项目，项目名称腹腔镜联合快速冰冻肝活检诊断胆道闭锁的研究，项目号20151140 （）
