临床与实验病理学杂志Issue(10)：1102-1106,5.DOI:10.13315/j.cnki.cjcep.2015.10.006
肝组织病理学评分在肝外胆道闭锁鉴别诊断中的意义
Values of histopathological assessment grading score in differential diagnosis of extrahepatic biliary atresia
赵丽 1胡晓丽 2赵林胜 1宋兰云 2詹江华1
作者信息
- 1. 天津市儿童医院 病理科，天津 300134
- 2. 天津市儿童医院普外科，天津 300134
- 折叠
摘要
Abstract
Purpose To study the values of liver histopathological assessment grading score in differential diagnosis between biliary atresia ( BA) and infantile hepatitis ( IHS) . Methods Thirty four cases of BA and sixteen cases of IHS were analyzed retrospectively, which were diagnosed by biopsy. A hepatic histopathological assessment grading score was developed. This consisted of eight features such as cholestasis, hepatocellular damage, bile duct proliferation, portal edema, portal inflammation, portal fibrosis, extramedullary hemopoiesis and multinucleated giant hepatocytes. The total scores were 24 points. All the cases were assessed one by one. Results The total scores of BA were significantly higher than that of IHS (P<0. 001). The frequencies of bile duct proliferation, portal fibrosis and portal edema were significantly higher in BA than that in IHS group, while the frequency of multinucleated giant hepatocytes was significantly higher in IHS than that in BA group. Conclusions This scoring system is helpful in differentiating BA from IHS.关键词
胆道闭锁/婴儿肝炎综合征/组织病理学评分Key words
biliary atresia/infantile hepatitis syndrome/histopathological assessment grading score分类
医药卫生引用本文复制引用
赵丽,胡晓丽,赵林胜,宋兰云,詹江华..肝组织病理学评分在肝外胆道闭锁鉴别诊断中的意义[J].临床与实验病理学杂志,2015,(10):1102-1106,5.
