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玻璃体腔注射康柏西普治疗湿性老年性黄斑变性及息肉状脉络膜血管病变

李迎春 樊映川

国际眼科杂志Issue(11):2009-2011,3.
国际眼科杂志Issue(11):2009-2011,3.DOI:10.3980/j.issn.1672-5123.2015.11.48

玻璃体腔注射康柏西普治疗湿性老年性黄斑变性及息肉状脉络膜血管病变

Effect of intravitreal Conbercept on wet age - related macular degeneration and polypoidal choroidal vasculopathy

李迎春 1樊映川1

作者信息

  • 1. 614001 中国四川省成都市,爱尔集团成都医学院附属康桥眼科医院
  • 折叠

摘要

Abstract

Abstract•AlM:To investigate the clinical effect of intravitreal conbercept on wet age-related macular degeneration ( wAMD) and polypoidal choroidal vasculopathy ( PCV) .•METHODS:Sixteen patients (16 eyes) with wAMD and 5 patients ( 5 eyes ) with PCV, both clinical diagnosed, were enrolled. All patients were treated with intravitreous conbercept. Additional treatments were administered if needed. Best corrected visual acuity ( BCVA ) , central retinal thickness ( CRT ) and choroidal thickness ( CT) were measured periodically.•RESULTS:The mean injection times at 6mo was 2. 93 ± 0. 27. The mean BCVAs were 0. 87 ± 0. 52 at baseline and 0. 74 ± 0. 43 at 6mo, which the difference was not statistically significant. The mean CRT significantly improved from 352. 24±131. 82 to 251. 73±69. 41μm at 6mo (P<0. 01). The mean CT reduced from 331. 93±115. 35 to 304. 72±104. 59μm (P<0. 05).•CONCLUSlON: lntravitreal conbercept can keep the visual acuity stable, reduce the retinal thickness and is safe on treating wAMD and PCV.

关键词

老年性黄斑变性/息肉样脉络膜血管病变/康柏西普

Key words

age - related macular degeneration/polypoidal choroidal vasculopathy/conbercept

引用本文复制引用

李迎春,樊映川..玻璃体腔注射康柏西普治疗湿性老年性黄斑变性及息肉状脉络膜血管病变[J].国际眼科杂志,2015,(11):2009-2011,3.

国际眼科杂志

OACSTPCD

1672-5123

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