护理学报Issue(15)：1-4,4.
癌痛患者强阿片类药物镇痛治疗继发便秘现况调查分析
Survey of Constipation Induced by Strong Opioid Drugs in Patients with Cancer Pain
杨丽华 1段培蓓 2侯庆梅 3修闽宁 3陈毓雯3
作者信息
- 1. 南京中医药大学 护理学院，江苏 南京 210029
- 2. 江苏省中医院护理部，江苏 南京 210029
- 3. 江苏省中医院肿瘤内科，江苏 南京 210029
- 折叠
摘要
Abstract
Objective To assess the prevalence, severity and impact of opioid-induced constipation (OIC) in cancer patients receiving opioid therapy for chronic pain. Methods Totally 107 cases of patients complaining pain (NRS score for moderate-severe pain), and receiving treatment with strong opioid were surveyed for the occurrence and severity of OIC and its impact on their quality of life. Results The most frequently-seen side effect of strong opioid drugs was constipation (91.6%) and most patients reported that OIC had severely negative impact on their overall quality of life. Conclusion The survey findings confirm that OIC occurs frequently among patients taking opioids for chronic cancer pain, which exerts negative impact on their quality of life. It is necessary to find a safe and acceptable approach specifically targeting the opioid-mediated mechanisms that cause constipation for patients.关键词
癌痛/阿片类药物/便秘Key words
cancer-related pain/opioid/constipation分类
医药卫生引用本文复制引用
杨丽华,段培蓓,侯庆梅,修闽宁,陈毓雯..癌痛患者强阿片类药物镇痛治疗继发便秘现况调查分析[J].护理学报,2013,(15):1-4,4.
