内蒙古民族大学学报（自然科学版）Issue(3)：334-336,3.
肺炎克雷伯菌的临床分布及耐药性分析
Analysis of the Clinical Distribution and Drug Resistance of Klebsiella Pneumoniae
王颖 1巴图德力根2
作者信息
- 1. 内蒙古民族大学蒙医药学院2009级研究生，内蒙古通辽 028043
- 2. 内蒙古民族大学 附属医院，内蒙古 通辽 028000
- 折叠
摘要
Abstract
Objective:Through experiment to know the situation of Gram-negative bacilli Klebsiella pneumoniae which producing extended-spectrum β-lactamases(ESBLs)in Tongliao area, to primarily grasp the status of resistant to commonly used antibiotics, and to provide an effective basis for clinical rational use of antibiotics. Methods:258 strains of Klebsiella pneumoniae were screened out from hospitalized patients in Affiliated Hospital of Inner Mongolia University for Nationalities from January 2012 to December 2012. By using double-disk synergy test to detecte the ESBLs produced by Gram-negative bacilli, applying KB method to do drug susceptibility test, and made a specific analysis of drug resistance for Klebsiella pneumoniae. The resistance results were statistically analyzed according to the software WHONET5.5, which was provided by the bacterial resistance monitoring network of World Health Organization, and the sensitivity and resistance analysis report were maken according to the standard which be set up by National Committee for Clinical Laboratory Standard (2009 edition). Results:The distribution of Klebsiella pneumoniae in ICU, respiratory medicine, neurosurgery were more. The drug resistance of Klebsiella pneumoniae and its enzyme production strains were strong, which brings a great deal of trouble for clinical treatment, imipenem is the first choice in the treatment of Klebsiella pneumoniae, besides, the strains are also relatively sensitive to cephalosporin compound preparation.Conclusion:The crossover drug programs can be used in clinic to avoid the emergence of resistant bacteria.关键词
肺炎克雷伯菌/耐药率Key words
Klebsiella pneumoniae/Drug resistance rates分类
医药卫生引用本文复制引用
王颖,巴图德力根..肺炎克雷伯菌的临床分布及耐药性分析[J].内蒙古民族大学学报（自然科学版）,2013,(3):334-336,3.
