热带亚热带植物学报Issue(6)：703-709,7.DOI:10.11926/j.issn.1005-3395.2015.06.016
南美蟛蜞菊中二萜化学成分的定性与定量分析研究
Qualitative and Quantitative Analysis of Diterpenoid Compounds in Sphagneticola trilobata (L.) Pruski
摘要
Abstract
In order to understand the chemical constituents of Sphagneticola trilobata (L.) Pruski, eight diterpenoids were isolated from the ethanol extract of its whole plants. On the basis of spectral data, they were identiifed as ent-16β,17-dihydroxy-9(11)-kauren-19-oic acid (1), cussovantonin B (2), ent-16-kauren-19-oic acid (3), ent-3β-hydroxy-16-kauren-19-oic acid (4), 16α-hydroxy-ent-kauran-19-oic acid (5), 2β,16α-dihydroxy-ent-kauran-19-oic acid (6), 3α-angeloyloxypterokaurene L3 (7) and pterokaurene L3 (8). Compound 4 were isolated from genus Sphagneticola for the first time, and compounds 1, 2 and 6 were isolated from S. trilobata for the first time. Compound 3 showed strong antibacterial activity against several bacteria and further inhibited signiifcantlyα-glucosidase activity in vitro. Based on structural derivation with pentalfuorobenzyl bromide coupled with GC-MS techniques, the contents of compound 3 in the stem and leaves of S. trilobata were (1.00±0.21) mg g–1 FW and (0.78±0.04) mg g–1 FW, respectively.关键词
南美蟛蜞菊/二萜化合物/抗菌/α-葡萄糖苷酶抑制剂/定量分析Key words
Sphagneticola trilobata/Diterpenoids/Antibacterial/α-Glucosidase inhibitor/Quantitative analysis引用本文复制引用
贾永霞,任慧,周忠玉,徐信兰,谭建文..南美蟛蜞菊中二萜化学成分的定性与定量分析研究[J].热带亚热带植物学报,2015,(6):703-709,7.基金项目
国家自然科学基金项目(31270406)；广东省自然科学基金项目(2014A030313742)；中国科学院仪器功能开发项目(YG2012050)资助 （31270406）
