四川精神卫生Issue(5)：407-410,4.DOI:10.11886/j.issn.1007-3256.2015.05.007
氟伏沙明联合思维阻断疗法治疗强迫症的效果观察
Clinical observation of fluvoxamine combined with thinking prevention therapy for obsessive compulsive disorder
周海平 1钟远惠 1何晓华 1徐炳聪1
作者信息
- 1. 510430 广东省广州市民政局精神病院
- 折叠
摘要
Abstract
Objective To observe the clinical efficacy of fluvoxamine combined with thinking prevention therapy on obsessive compulsive disorder. Methods A total of 56 patients with obsessive thinking and obsessive - compulsive disorder confirmed by ICD -10 diagnostic criteria were randomly divided into single fluvoxamine group and fluvoxamine combined with thinking prevention therapy group,and observed for 12 weeks. Yale - Brown Obsessive Compulsive Scale(Y - BOCS)was used to evaluate the mental status of subjects before treatment and the 4th ,8th ,12th week after the treatment. Meanwhile,the life quality of the subjects was evaluated by the Generic Life Quality Inventory(GQOLI - 74)at the same intervals. Results Before treatment,there was no statistically significant difference among Y - BOCS and GQOLI - 74 scores of the two groups(P > 0. 05). 4 weeks after treatment,Y - BOCS scores of the two groups was lower than those of before treatment,the difference was statistically significant(P < 0. 05). 8 weeks after treatment,the Y - BOCS score of the combined group decreased more than the control group,the difference was statistically significant(P < 0. 05). 12 weeks after treatment,the combined group psychological function and social function of GQOLI - 74 score were higher than that of control group(P < 0. 05). Conclusion Fluvoxamine combined with thinking prevention therapy has better efficacy than use fluvoxam-ine for patients with obsessive thinking and obsessive - compulsive disorder,and it can improve the patient′s quality of life.关键词
氟伏沙明/思维阻断疗法/强迫症Key words
Fluvoxamine/Thought prevention therapy/Obsessive compulsive disorder分类
医药卫生引用本文复制引用
周海平,钟远惠,何晓华,徐炳聪..氟伏沙明联合思维阻断疗法治疗强迫症的效果观察[J].四川精神卫生,2015,(5):407-410,4.
