四川医学2015，Vol.36Issue(10)：1473-1475,3.DOI:10.16252/j.cnki.issn1004-0501-2015.10.035
凉山地区女性宫颈感染人乳头瘤病毒基因型分析
Analysis of the Genotypes of HPV Genotypes in Women with Cervical Infection in Liangshan Area
黄静 1李俊如 1朱波1
作者信息
- 1. 凉山彝族自治州第一人民医院,四川 西昌615000
- 折叠
摘要
Abstract
Objective To study infection situation and distribution of human papilloma virus( HPV) genotype from women with uterine cervical epithelial cells in Liangshan Area. Methods 2643 patients's uterine cervical cast-off cells from different age in January-August 2014 were detected and typed to 23 genotypes by dot blot hybridization reverse-gene chip. Results The posi-tive rate of HPV from 2643 patients was 25. 31%, about 699 patients;the single positive infection was 18. 01%, about 476 pa-tients;while the infection of two or more kinds of HPV subtypes was 7. 30%,about 193 patients. Statistics 958 cases depended on ethnicity. The positive rate of the Han people was 24. 16%(172/712),Yi people was 29. 15%(65/223),There was no significant difference in the national analysis. From 23 genotypes of HPV,the positive patients of low-risk types were 167,among them the 81 genotype was most;the positive rate of high-risk types were 763,the top five positive cases were 52 genotype、16 genotype、58 geno-type、53 genotype and 18 genotype. Moreover,the patients with positive HPV in the age group ≤20 years(38. 78%) and ≥ 51 years(33. 21%)were higher. Infection detection comparative difference was statistically significant( =22. 99 P<0. 01). Con-clusion Female uterine cervical HPV infection had a unique geographical and age distribution characteristics in Liangshan Area, There was no significant difference between ethnicity.关键词
人乳头瘤病毒/基因分型Key words
human papilloma virus/genotyping分类
医药卫生引用本文复制引用
黄静,李俊如,朱波..凉山地区女性宫颈感染人乳头瘤病毒基因型分析[J].四川医学,2015,36(10):1473-1475,3.
