肿瘤预防与治疗Issue(5)：249-252,4.DOI:10.3969/j.issn.1674-0904.2015.05.002
预后营养指数在胃癌患者术后预后判断中的应用
The Application of Prognostic Nutritional Index in Predicting the Outcomes of Gastric Cancer Patients Accepted Gastrectomy
李洲1
作者信息
- 1. 四川省自贡市第一人民医院，四川自贡 643000
- 折叠
摘要
Abstract
Objective:To explore the application of prognostic nutritional index (PNI)in predicting the postoper-ative complications and long-term outcomes in gastric cancer patients undergoing gastrectomy.Methods:The data for 128 patients with pathologically proved gastric cancer who accepted gastrectomy in our hospital between January 2006 and June 2014 were extracted and analyzed.Subjects were divided into two groups according to the cutoff value of the PNI.Clinico-pathological features were compared between the two groups and potential prognostic factors were analyzed.The Cox propor-tional hazard model was used to explore the influencing factors.Results:The optimal cutoff value of the PNI was set at 50.1 ,and patients with PNI≥50.1 and those with PNI<50.1 were classified into PNI-high and PNI-low groups,respec-tively.Patients in the PNI-low group were more likely to be older than 65 years old,had larger tumor size (≥5cm)and deeper invasion depth (T3 and T4 ),had lymph node metastasis (N)and higher incidence of postoperative complications when comparing with those in the PNI-high group.The multivariate analyses showed that PNI value,depth of invasion, lymph node metastasis and postoperative complications were independent factors in predicting overall survival rate of pa-tients who underwent gastrectomy.Conclusion:PNI is recommended to identify the prognosis of gastric cancer patients ac-cepted gastrectomy with its easy way of calculation.关键词
预后营养指数/胃癌/预后Key words
Prognostic Nutritional Index/Gastric Carcinoma/Prognosis分类
医药卫生引用本文复制引用
李洲..预后营养指数在胃癌患者术后预后判断中的应用[J].肿瘤预防与治疗,2015,(5):249-252,4.
