药学研究Issue(10)：584-587,4.
硫酸氢氯吡格雷阿司匹林片的处方工艺研究
Study on preparation process of Clopidogrel Bisulfate and Aspirin Tablet
李欣 1邢雪敏 2颜红1
作者信息
- 1. 山东省药学科学院，山东省化学药物重点实验室，山东 济南 250101
- 2. 山东福瑞达医药集团公司，山东省黏膜与皮肤给药技术重点实验室，山东 济南 250101
- 折叠
摘要
Abstract
Objective To study the preparation technology of Compound Clopidogrel Bisulfate and Aspirin Tab-let. Methods The orthogonal design was adopted to screen the formula technology. Powder direct tableting process prepara-tion of double - deck tabtet was used. The screened optimal formula was performed and the verification and quality investiga-tion. Results The tablet weight variation,dissolution rate,content and related substances of the samples were all in accord-ance with the corresponding requirements. The technology was rational and the quality was controllable. Conclusion The preparation technology of Compound Clopidogrel Bisulfate and Aspirin Double - deck Tablet was simple with stable quality and suitable for industrial production.关键词
硫酸氢氯吡格雷/阿司匹林/双层片/制备Key words
Clopidogrel Bisulfate/Aspirin/Double - deck tablet/Prepartion分类
医药卫生引用本文复制引用
李欣,邢雪敏,颜红..硫酸氢氯吡格雷阿司匹林片的处方工艺研究[J].药学研究,2015,(10):584-587,4.
