药学研究Issue(12)：726-730,5.
氧化应激对血管活性物质的影响及其机制研究进展
Research progress of the effect and mechanism of oxidative stress on vasoactive substances
杨文娟 1洪泽 1严思敏 1丁启龙1
作者信息
- 1. 中国药科大学药学医学基础实验教学中心，江苏 南京 211198
- 折叠
摘要
Abstract
Hypertension is one of the most common cardiovascular in the world and it is one of the most important risk factors for developing cardiovascular disease. It is urgent to findthe molecular mechanisms contributing to the initiation of hy-pertension and the new therapeutic strategy against hypertension. Vascular endothelial controls maintenance of vascular ho-meostasis by releasing endothelium - derived relax and constriction factor. A plethora of studies had demonstrated that the importance of oxidative stress in developing of hypertension. Oxidative stress can change the contracting and relaxing of vas-cular by affecting the synthesis of vasoactive substances. This review aimed to highlight oxidative stress to the endothelial function by influence of synthesis of NO,PGI2 ,ET - 1 and TXA2 .关键词
氧化应激/一氧化氮/前列环素/内皮素 - 1/血栓素 A2Key words
Oxidative stress/NO/PGI2/ET - 1/TXA2分类
医药卫生引用本文复制引用
杨文娟,洪泽,严思敏,丁启龙..氧化应激对血管活性物质的影响及其机制研究进展[J].药学研究,2015,(12):726-730,5.
