山东医药2015,Vol.55Issue(41):16-19,4.DOI:10.3969/j.issn.1002-266X.2015.41.006
脓毒症急性肾损伤患者肾功能恢复的影响因素
Influence Factors of Renal Function Recovery in Sepsis-Related Acute Kidney Injury Patients
摘要
Abstract
Objective To discuss the influence factors of renal function recovery in sepsis-related acute kidney injury patients.Methods To analysis the sex, age, source, primary infection site, improving global outcomes ( KDIGO) stand-ard, acute physiology and chronic health evaluation-Ⅱ ( APACHE-Ⅱ) score in first 24 hours admitted to hospital, me-chanical ventilation, oliguria or anuria, organ functional failure, renal replacement therapy( RRT) , and renal function re-covery of 193 sepsis-related acute kidney injury patients during the hospital.Results Totally 193 cases, the recovery group of 110 cases, and non-recovery group of 83 cases.According to comparison of variables between the two groups, that age, KDIGO standard, APACHE-Ⅱscore, mechanical ventilation, oliguria, number of organ dysfunction and RRT were statistically significant ( P<0.05).Logistic regression analysis model showed that older, higher KDIGO standard, A-PACHEⅡscore, more the number of organ failure, mechanical ventilation, oliguria were the independent risk factors( OR=7.676, 14.404, 11.542, 6.137, 18.235, 10.333, all P<0.05), while the RRT was the recovery factors of renal function (OR=0.217,P<0.05).Conclusions Renal function recovery is related with many factors, such as the age, KDIGO standard, APACHE-Ⅱscore, number of organ dysfunction, mechanical ventilation, oliguria and RRT of sepsis-re-lated AKI patients.关键词
脓毒症/急性肾损伤/肾功能/影响因素Key words
sepsis/acute kidney injury/renal function/influence factors分类
医药卫生引用本文复制引用
刘培,吴京秦,段美丽..脓毒症急性肾损伤患者肾功能恢复的影响因素[J].山东医药,2015,55(41):16-19,4.基金项目
北京市科技计划课题资助项目( Z121107001012124 ). ( Z121107001012124 )