山西中医学院学报Issue(4):16-18,3.
炙桂枝与肉桂对普萘洛尔致心动过缓大鼠Na+-K+-ATP酶活性研究
Effect of prepared cassia twigs and cassia on Na+-K+-ATPase activity in rats with bradycardia caused by propranolol
摘要
Abstract
Objective:To study effect of prepared cassia twigs and cassia on Na +-K +-ATPase activity in rats with bradycardia caused by propranolol. Methods:70 rats were randomly divided into prepared cassia twig group,prepared cassia twig model group,cassia group,cassia model group,blank group,propranolol group and atropine group (n=10). Model rats were constructed by propranolol.7 d after treatment,heart rate and activity of Na+-K+-ATPase were observed. Results:Compared with propranolol group,the drop rate of 30 min heart rate was decreased in prepared cassia twig model group and cassia model group (P<0.01). The activity of Na+-K+-ATPase in prepared cassia twig model group and cassia model group was higher than that in propranolol group(P<0.05,P<0.01). Conclusion:Both prepared cassia twig and cassia can obviously increase the heart rate in bradycardia rats caused by propranolol through improving the activity of Na+-K+ATpase.关键词
心动过缓/炙桂枝/肉桂/普萘洛尔/Na+-K+-ATP酶Key words
bradycardia/prepared cassia twig/cassia/propranolol/Na+-K+-ATPase分类
医药卫生引用本文复制引用
罗琳,陈一江..炙桂枝与肉桂对普萘洛尔致心动过缓大鼠Na+-K+-ATP酶活性研究[J].山西中医学院学报,2015,(4):16-18,3.基金项目
浙江中医药管理局科研课题 ()