神经病学与神经康复学杂志Issue(2)：87-89,3.
阴性或阳性症状为主的精神分裂症患者的P300亚成份分析
Analysis on event-related potential P300 subcomponents in schizophrenia patients with positive or negative symptoms
摘要
Abstract
Objective To explore the value of event-related potential P300 subcomponents in the evaluation of cognitive function in schizophrenia patients mainly with positive or negative symptoms . Methods The P3a and P3b were tested in 56 schizophrenia patients mainly with negative symptoms ( the negative group ) and 49 schizophrenia patients mainly with positive symptom ( the positive group ) respectively , and the findings were compared with that from the control group. Results In negative group, the mean latency of P3a at FZ was obviously extended than that in the positive group (P<0.01), the mean amplitudes of P3a at FZ and CZ as well as the mean amplitudes of P3b at CZ and PZ were significantly lower than those from the positive group and the control group ( P<0.01, P<0.05, respectively ) . Conclusion Schizophrenia patients mainly with negative symptoms have more impaired cognitive functions than those patients mainly with positive symptoms and which could be sensitively evaluated by the P 3a assessment .关键词
精神分裂症/认知障碍/P3a/P3bKey words
schizophrenia/cognitive dysfunction/P3a/P3b分类
医药卫生引用本文复制引用
董日霞,杨建功,杜向东,杨勇,殷光中,徐晓文..阴性或阳性症状为主的精神分裂症患者的P300亚成份分析[J].神经病学与神经康复学杂志,2013,(2):87-89,3.基金项目
苏州市科技计划指导项目 （）
