世界中医药Issue(10)：1604-1606,1610,4.DOI:10.3969/j.issn.1673-7202.2015.10.039
基于关联规则与熵聚类的健脾类中成药组方规律研究
Analysis on Composition Rules of Chinese Patent Drugs with Tonifying Spleen Based on Association Rules and Clustering Algorithm
摘要
Abstract
Objective:To investigate composition rules of Chinese patent drugs with tonifying spleen.Methods:The prescriptions of Chinese patent drugs with tonifying spleen in “The New National Medicine”were collected to build a database.The methods of association rules with apriori algorithm and complex system entropy cluster were used to achieve the frequency of medicines and as-sociation rules between drugs.Results:The data-mining results indicated that in the prescriptions of Chinese patent drugs with ton-ifying spleen,the most frequency used drugs were Poria Cocos Wolff,Rhizoma Atractylodis Macrocephalae,Radix Glycyrrhizae, Radix Codonopsitis,Pericarpium Citri Reticulatae.The most common drug combinations were”Rhizoma Atractylodis Macrocepha-lae,Poria Cocos Wolff”,”Radix Glycyrrhizae,Poria Cocos Wolff”,”Radix Glycyrrhizae,Rhizoma Atractylodis Macrocephalae”. The drugs with a high degree confidence coefficient of association rules include “Pericarpium Citri Reticulatae->Semen Dolicho-ris”,“Pericarpium Citri Reticulatae->Pinellia ternata”.Conclusion:There are not only the common drugs tonifying spleen,but also drugs regulating the flow of vital energy,removing obstruction toit,and helping digest.关键词
健脾药/关联规则/熵聚类Key words
Chinese patent drugs/Tonifying spleen/Association Rules/Clustering Algorithm分类
医药卫生引用本文复制引用
金燕萍,吴嘉瑞,张冰,杨冰,周唯,张晓朦..基于关联规则与熵聚类的健脾类中成药组方规律研究[J].世界中医药,2015,(10):1604-1606,1610,4.基金项目
国家科技支撑计划课题（编号2007BAI10B01）；北京市中医药科技发展基金课题（编号JJ-2010-70）；北京中医药大学科研创新团队项目资助（编号2011-CXTD-14）；北京中医药大学“重点学科”开放课题（编号2013-ZDXKKF-19）；北京市与中央在京高校共建项目（编号BJGJ1420）；北京中医药大学与北京灸道堂中医研究院横向合作课题 （）
