生物技术通报Issue(11)：27-34,8.DOI:10.13560/j.cnki.biotech.bull.1985.2015.11.002
人类长链非编码RNA相关SNP鉴定与功能预测的研究进展
Research Progress of the Human Long Non-coding RNA Related SNP Identification and Function Prediction
龚静 1柳纯洁 2缪小平 1郭安源2
作者信息
- 1. 华中科技大学公共卫生学院，武汉 430030
- 2. 华中科技大学生命科学与技术学院，武汉 430074
- 折叠
摘要
Abstract
Long non-coding RNA(lncRNA)is a class of RNA, whose length is greater than 200 nucleotides and it does not show any protein-coding potential. The latest research shows that lncRNA plays function widely in the development of plants and animals, as well as in various diseases. There have been a series of reports on the discovery, prediction method, function study of lncRNA. Here, we reviewed the study of lncRNA related SNPs, including their identification and functional prediction. A comprehensive review of the bioinformatics methods and databases about the lncRNA related SNP was provided. These reviews may help to provide a new point of view for lncRNA research and a hint for the prediction, diagnosis and treatment of complex diseases based on lncRNA.关键词
长链非编码RNA/生物信息学/单核苷酸多态性/数据库Key words
long non-coding RNA/bioinformatics/single nucleotide polymorphism/database引用本文复制引用
龚静,柳纯洁,缪小平,郭安源..人类长链非编码RNA相关SNP鉴定与功能预测的研究进展[J].生物技术通报,2015,(11):27-34,8.
