生物技术通报Issue(11)：35-42,8.DOI:10.13560/j.cnki.biotech.bull.1985.2015.11.006
家养动物基因组拷贝数变异研究进展及其育种应用展望
Progress and Prospects in Domestic Animals and Breeding:a Review of Genomic Copy Number Variations
摘要
Abstract
The significant progress ofde novo assembly and re-sequencing of agricultural animal genomes, promoted the discovery of abundant genetic variations. Global variations mainly include single nucleotide polymorphisms(SNPs)and copy number variations(CNVs). Unlike SNPs, which have been widely studied and applied as molecular marker in breeding, fewer CNVs have been detected and experimental validated. Therefore, CNVs rarely serve as molecular markers in breeding. However, the proportion of genome variation ascribed to CNVs are far larger than to SNPs. So CNVs may have great impacts on agronomic traits. Recently, CNV is on the cutting edge of the research studies as well as applications in livestock and poultry breeding. In this review, we discuss the research progress of CNV, and its prospects for breeding domestic animals.关键词
家养动物/基因组/拷贝数变异/育种/经济性状Key words
domestic animal/genome/copy number variation/breeding/economic trait引用本文复制引用
程红,姜雨..家养动物基因组拷贝数变异研究进展及其育种应用展望[J].生物技术通报,2015,(11):35-42,8.基金项目
陕西省科技新星资助项目 （）
