陕西师范大学学报（自然科学版）Issue(6)：100-105,6.DOI:10.15983/j.cnki.jsnu.2015.06.264
负重爬梯与负重跑台运动对大鼠股骨微结构及力学特性的影响
The influence of weight-bearing treadmill running and climbing-ladder exercise on micro-structure and biomechanical properties of rats femur
摘要
Abstract
The aim of the study was to investigate the micro-structure and biomechanical proper-ties of femur of rats that treated with weight-bearing treadmill running and climb ladder,and e-valuating the meaning of two exercise to the femur.Twenty-eight male Sprague-Dawley rats were randomly divided into 3 groups:weight-bearing treadmill group (WR),weight-bearing climbing ladder group (CL),control group (CON).WR group were trained,running on a motor-driven treadmill at a speed of 15 m/min (0 incline)bearing with 35% their body-weight mass added,two minutes running and two minutes intervals between each 40 minutes cycle,6 days/week.LC group were trained three cycle (10times/cycle)with the same weight,two minutes intervals.Af-ter trained with 8 weeks,all rats were euthanized by pentobarbital sodium and the femur were harvested for Micro-CT and three-point test.The results is revealed by Micro-CT.Comparing with the CON group,the trabecular number (Tb.N)and bone volume over total volume (BV/TV)of the WR group and CL group increased significantly.Meanwhile the trabecular separation (Tb.Sp)and structure model index (SMI)decreased significantly.The three-point test showed that,the Modulus of Elasticity (MOE)of the CL group were significantly higher than the WR group and CON group.The maximum loading (ML)of the WR group and CL group were signifi-cantly higher than the CON group.And the stiffness (slope linear)in the WR group increased significantly compared with the CON group.The results suggested that both ways of weight-bearing training can improve the micro-structure and the biomechanical properties in different de-grees after the 8 weeks of weight-bearing training,and the weight-bearing climbing training is better than the weight-bearing treadmill training.关键词
负重跑台/负重爬梯/骨微结构/力学特性/大鼠Key words
weight-bearing treadmill running/climbing-ladder exercise/bone micro-structure/bi-omechanical properties/rats分类
社会科学引用本文复制引用
唐量,高小航,赵新娟,张静,孙丽君..负重爬梯与负重跑台运动对大鼠股骨微结构及力学特性的影响[J].陕西师范大学学报（自然科学版）,2015,(6):100-105,6.基金项目
国家自然科学基金（30900710）；陕西省自然科学基金（2015JQ2051）；中央高校基础科研项目 （）
