陕西医学杂志Issue(11)：1461-1463,3.DOI:10.3969/j.issn.1000-7377.2015.11.007
共焦显微镜下不同程度干眼角膜内树突状细胞观察研究∗
Studies on the dendritic cells in the cornealepithelium of dry eye in vivo confocal microscopy
摘要
Abstract
Objective:To objective the density of dendritic cellsand the proportion of activated cells of dif-ferent degree of dry eye patients in vivo confocal microscopy,so as to investigate the mechanism of dry eye ,to pro-vide the basis for clinical diagnosis and treatment of dry eye.Methods:A case series with 60 consecutive cases of dif-ferent degrees dry eye patients was investigated,examined with confocal microscopy in vivo,and at the same time the density of dendritic cells and the proportion of activated cells was recorded and analyzed with SPSS1 7.0 .Results:In mild dry eye,dendritic cell density was 26.7 ± 8.8/ mm2 ,with activated cell 29.0 ± 3.7%;In moderate dry eye dendritic cell density was 69.6 ± 1 1.1 / mm2 ,with activate cell 83.5±7.6%;In severe dry eye dendritic cell den-sity was 212.2 ± 31.0 / mm2 ,with activate cell 97.8±1.9%.The data showed that the corneal dendritic cell den-sityand the proportion of activated cells were found increased in more severe dry eye,with statistically significant difference .Conclusion:In vivo confocal microscope,dendritic cells is an important sign of dry eye inflammation.The proportion of activated cells and its density can be used as effective indicators to assess the degree of dry eye.关键词
显微镜检查,共焦/干眼病/诊断/树突细胞/角膜Key words
Microscopy,confocal/Xerophthalmia/diagnosis/Dendritic cells/Cornea分类
医药卫生引用本文复制引用
朱海峰,程燕,吴洁,程钰,王双勇..共焦显微镜下不同程度干眼角膜内树突状细胞观察研究∗[J].陕西医学杂志,2015,(11):1461-1463,3.基金项目
陕西省社会发展科技攻关项目(2015SF206) （2015SF206）
