实用医学杂志Issue(17)：2868-2870,3.DOI:10.3969/j.issn.1006-5725.2015.17.033
经鼻持续气道正压通气优先策略在重症毛细支气管炎中的应用
Clinical application of nCPAP as pre-emptive ventilatory support strategy in severe bronchiolitis
沈玉才 1王斌 2巢伟聪 1许志松 1邝勇华 1陈剑锋2
作者信息
- 1. 510900 广州市，南方医科大学第五附属医院PICU
- 2. 510282 广州市，南方医科大学珠江医院儿科
- 折叠
摘要
Abstract
Objective To investigate the effect of nCPAP as pre-emptive ventilatory support strategy in severe bronchiolitis. Methods A retrospective analysis was made on cases with nCPAP as pre-emptive ventilatory support strategy for severe bronchiolitis in PICU of our hospital from August 2012 to September 2014. Results Seventy-nine children received nCPAP therapy in our PICU. Overall, nCPAP was successful performed in 69 children, 10 patients required intubations. PaO2 and PaO2/FiO2 in patients received intubations were lower than those in patients received only nCPAP before treatment (P < 0.05). There were significant improvements in PaCO2, PaO2, PaO2/FiO2, respiratory rate and heart rate in the patients received only nCPAP at 12 hours and 24 hours post-treatment (P < 0.05). For the 69 patients with hypercapnia received only nCPAP, PaCO2 was significantly reduced at 2 hours, 12 hours and 24 hours post-treatment (P < 0.01). Conclusion Clinically, nCPAP could improve the oxygenation and hypercapnia of patients with severe bronchiolitis. However, these patients, who suffered from severe bronchiolitis with minor PaO2 or PaO2/FiO2, appeared to require intubation as soon as possible.关键词
毛细支气管炎/经鼻持续气道正压通气/机械通气/婴儿Key words
Nasal continuous positive airway pressure/Bronchiolitis/Ventilation/Infant引用本文复制引用
沈玉才,王斌,巢伟聪,许志松,邝勇华,陈剑锋..经鼻持续气道正压通气优先策略在重症毛细支气管炎中的应用[J].实用医学杂志,2015,(17):2868-2870,3.
