武警医学Issue(10)：1001-1003,1006,4.
Ⅰb和Ⅱ期宫颈癌术后调强放疗的疗效
Efficacy ofⅠb and Ⅱ stage cervical cancer treated by intensity-modulated radiotherapy after surgery
杨健 1许新明 1刘颖 1徐刚2
作者信息
- 1. 061000，沧州市人民医院放疗科
- 2. 100142，北京大学肿瘤医院暨北京市肿瘤防治研究所放疗科
- 折叠
摘要
Abstract
Objective To analyze the efficacy and treatment related toxicities for patients with Ⅰb andⅡstage cervical canc-er treated by Intensity Modulated Radiation Therapy (IMRT).Methods From January 2008 to February 2012,83 patients with stageⅠb-Ⅱpostoperative cervical cancer were retrospectively analyzed .The clinical target volume received a dose of 50 Gy/25 fractions in all patients.All patients were treated by IMRT and cisplatin-based chemotherapy for 2-4 cycles.Results Treatment was completed successfully in all patients.The follow-up rate was 100%.In all patients, the 3-year overall survival (OS) rate was 89.2%, with dis-ease-free survival (DFS) rate of 83.1%and pelevic local control (LC) rate of 85.5%.The 3-year OS rates were 50%and 91%for patients with adenocarcinoma and squamous carcinoma (χ2 =9.65,P=0.002).The incidences of grade 1-2 rectal toxicity , urinary toxicity and myelosuppression were 10.34%,10.34%and 58.62%.There were no grade 4 toxicities.Conclusions The postoperative cervical cancer patients with poor prognostic factors who undergo IMRT can achieve high overall survival rates ,local control rates and tolerable toxicities .关键词
宫颈肿瘤/放化疗法/调强放射治疗/预后Key words
cervical neoplasms/radiochemotherapy/intensity modulated radiation therapy/prognosis分类
临床医学引用本文复制引用
杨健,许新明,刘颖,徐刚..Ⅰb和Ⅱ期宫颈癌术后调强放疗的疗效[J].武警医学,2015,(10):1001-1003,1006,4.
