物理学报Issue(8):1-7,7.DOI:10.7498/aps.62.084708
观测包膜微泡在超声场中的动力学行为
Observation of encapsulated microbubble dynamics in ultrasound field∗
摘要
Abstract
Using a long-distance microscope imaging system and a lock-in phase integrate technique, optical measurements demonstrate that the evolutional behaviors of a phospholipid-shelled micro-bubble, a kind of ultrasound contrast agent, under two ultrasound frequencies and different pressures. Dozens of frames of an oscillating microbubble for one acoustic cycle are captured. The experimental data of micro-bubble diameter are fit by the numerical calculations of the Hoff model and the Rayleigh-Plesset model, respectively. The results show the good agreement between experimental data and the theoretical calculation in the Hoff model. In addition, the spectral analysis based on the experimental data indicates that the relative intensity of the second harmonic increases with the driving pressure amplitude.关键词
包膜微泡/锁相积分拍摄方法/频谱Key words
encapsulated microbubbles/lock-in integrate imaging method/spectra引用本文复制引用
梁金福,陈伟中†,邵纬航,周超,杜联芳,金利芳..观测包膜微泡在超声场中的动力学行为[J].物理学报,2013,(8):1-7,7.基金项目
国家杰出青年科学基金(批准号:60925017)、国家自然科学基金(批准号:10990100,60836003,60976045,61176126)和清华信息科学与技术国家实验室(筹)学科交叉基金资助的课题.*Project supported by the National Science Fund for Distinguished Young Scholars, China (Grant No.60925017), the National Natural Science Foun-dation of China (Grant Nos.10990100,60836003,60976045,61176126), and the Cross-discipline Foundation of Tsinghua National Laboratory for Information Science and Technology, China (批准号:60925017)