中国组织工程研究Issue(5)：907-912,6.DOI:10.3969/j.issn.2095-4344.2013.05.022
女性膀胱癌患者原位回肠和乙状结肠尿流改道效果的比较☆
Comparison of clinical efficacy between orthotopic ileal neobladder and orthotopic sigmoid neobladder in female bladder cancer patients☆
王海峰 1王剑松 1徐鸿毅 1石永福 1左毅刚 1杨德林1
作者信息
- 1. 昆明医科大学第二附属医院泌尿外科，云南省泌尿外科研究所，云南省昆明市650101
- 折叠
摘要
Abstract
BACKGROUND: The orthotopic urinary diversion after radical cystectomy of bladder cancer has good urinary continence. However, there are few reports about the clinical efficacy and fol ow-up of orthotopic ileal neobladder and orthotopic sigmoid neobladder in female bladder cancer patients. OBJECTIVE: To compare the clinical efficacy of orthotopic ileal neobladder and orthotopic sigmoid neobladder in female bladder cancer patients. METHODS: The clinical data of the female patients with bladder cancer who were treated with orthotopic ileal neobladder (ileal group, n=29) and orthotopic sigmoid neobladder (sigmoid group, n=23) from 1996 to 2008 were retrospective analyzed. The intraoperative and postoperative conditions, urodynamics, urinary continence, pouch-related complications of the patients in two groups were compared. RESULTS AND CONCLUSION: The average fol ow-up time was 57 months in the ileal group, and 55 months in the sigmoid group. There was no difference in intraoperative blood loss and postoperative urinary continence between two groups, and there were significance differences in operative time, postoperative out-of-bed activity and the orthotopic neobladder’s capacity between two groups (P < 0.05). The early and late pouch-related complication rates in the ileal group were higher than those in the sigmoid group. In the ileal group, tumor recurred in two patients, and no tumor recurred in the sigmoid group. It indicates that orthotopic ileal neobladder and orthotopic sigmoid neobladder in female patients are both safe and effective to achieve satisfactory clinical outcomes.关键词
器官移植/器官移植基础实验/尿流改道术/回肠代膀胱/乙状结肠代膀胱/尿动力学/控尿能力/女性/膀胱癌/疗效Key words
organ transplantation/basic experiments of organ transplantation/urinary diversion/ileal neobladder/sigmoid neobladder/urodynamic/urinary continence/women/bladder cancer/efficacy分类
医药卫生引用本文复制引用
王海峰,王剑松,徐鸿毅,石永福,左毅刚,杨德林..女性膀胱癌患者原位回肠和乙状结肠尿流改道效果的比较☆[J].中国组织工程研究,2013,(5):907-912,6.
