中国组织工程研究Issue(7)：1185-1188,4.DOI:10.3969/j.issn.2095-4344.2013.07.009
扩张皮肤移植后的生物力学变化
Biomechanical changes following expanded skin grafting
田宝祥 1刘凤彬 1杨雄 1蔺海龙 1刘洋 1樊华 1魏纯琳1
作者信息
- 1. 吉化集团公司总医院烧伤整形科北华大学第二附属医院，吉林省吉林市132022
- 折叠
摘要
Abstract
BACKGROUND: A skin soft tissue dilator is implanted into the normal skin, generating pressure to expand the skin soft tissue to produce “extra” skin soft tissues by increasing the capacity within the dilator. This technique has become a basic method in skin tissue engineering. OBJECTIVE: To establish a dog model of expanded skin grafting and to observe the short-term and long-term regular patterns fol owing skin expansion and grafting. METHODS: Twelve adult dogs were randomly selected. Four dilators of 150 mL, two of which did not work as controls, were implanted into the back of dogs. Skin stress-strain, stress relaxation, and ultimate tensile strength were detected and compared at different periods after skin expansion. RESULTS AND CONCLUSION: The skin viscoelasticity and intensity reduced significantly after skin expansion. The viscoelasticity could restore the normal value within 6 months, and the intensity, however, had a slower recovery. As biomechanical changes occur provisional y and can be restored after skin grafting, a more attention should be paid in clinic.关键词
组织构建/组织构建与生物力学/皮肤移植/生物力学/皮肤黏弹性/扩张器/皮肤应力/应力松弛/抗拉强度Key words
tissue construction/tissue construction and biomechanics/skin grafting/biomechanics/skin viscoelasticity/dilator/skin stress/stress relaxation/tensile strength分类
医药卫生引用本文复制引用
田宝祥,刘凤彬,杨雄,蔺海龙,刘洋,樊华,魏纯琳..扩张皮肤移植后的生物力学变化[J].中国组织工程研究,2013,(7):1185-1188,4.
