中国组织工程研究Issue(7)：1281-1288,8.DOI:10.3969/j.issn.2095-4344.2013.07.024
一氧化氮对末端病中骨及韧带的影响**★
Nitric oxide effects on the bone and ligaments in enthesiopathy
摘要
Abstract
BACKGROUND: Nitric oxide is the most important regulatory factor and an important information transmission between biological molecules, which is one of the important influence factors for enthesiopathy. OBJECTIVE: Through viewing articles related to nitric oxide and enthesiopathy, to review the function of nitric oxide on enthesiopathy. METHODS: An online search of CNKI and High Wire databases was performed for articles related to “nitric oxide, enthesiopathy” by the first author. Articles published with the keywords of “nitric oxide, enthesiopathy” in Chinese and English were included. Articles related to the functions of nitric oxide on enthesiopathy were selected. Articles published recently or in the authorized journals were of priority. A total of 135 articles were col ected in the initial research, and 30 of them were retained according to inclusion and exclusion criteria. RESULTS AND CONCLUSION: Although there different views about whether nitric oxide is involved in enthesiopathy and repair process at the same time, nitric oxide is closely related to the pathologic process of enthesiopathy. A rat model of enthesiopathy has proved that repeated mechanical stress can induce the inflammatory disorder and degeneration of terminal tissues, but scholars about the cel and molecular biological mechanisms are not identical of views. It is unclear about what kind of relations there are between each factors and how external factors and nitric oxide influence these relations to cause enthesiopathy.关键词
组织构建/组织构建学术探讨/末端病/一氧化氮/信号通路/骨/肌腱/韧带/跟腱/关节囊/自由基/省级基金Key words
tissue construction/academic discussion of tissue construction/enthesiopathy/nitric oxide/signal pathway/bone/tendon/ligament/Achil es tendon/joint capsule/free radicals/provincial grants-supported paper分类
医药卫生引用本文复制引用
王文军,王丹,鲍捷,李盛村,程龙,王国祥..一氧化氮对末端病中骨及韧带的影响**★[J].中国组织工程研究,2013,(7):1281-1288,8.基金项目
江苏省2012年度普通高校研究生科研创新计划项目(CXLX12_0758)；2011江苏省省属高校自然科学研究面上项目(11KJD320001)。Supported by：the 2012 Innovative Research Plan for the Postgraduate in Jiangsu Province, No. CXLX12_0758* （CXLX12_0758）
the Natural Science Program for Universities in Jiangsu Province, No.11KJD320001* （）
