中国组织工程研究Issue(9)：1687-1694,8.DOI:10.3969/j.issn.2095-4344.2013.09.025
正电子发射计算机断层显像/核磁共振：分子影像学技术新进展**★
Positron emission tomography computed tomography/magnetic resonance imaging:A new progress of molecular imaging technique
摘要
Abstract
BACKGROUND: Positron emission tomography can reflect the cel metabolism and functional changes of cells at the molecular level. Magnetic resonance imaging can obtain images with higher soft-tissue contrast and better spatial resolution without ionizing radiation. With the fast development of multimodality molecular imaging techniques, positron emission tomography/magnetic resonance imaging as a multimodality molecular imaging technique can provide the molecular, morphological and functional information, so its clinical application is an anticipating focus of medical molecular imaging.OBJECTIVE: To overview the progress and problems meet in the development of positron emission tomography/magnetic resonance imaging and to get a clear prospect of its potential clinical and scientific application. METHODS: The CNKI database, SpringerLink database and PubMed database were searched by the first author for the related articles from January 2000 to June 2012. The English key words were “PET/MRI” and“multimodality molecular imaging or image fusion”, and the Chinese key words were “molecular imaging” and“image fusion”. The articles related to positron emission tomography/magnetic resonance imaging multimodality molecular imaging technique were selected, and for the articles in the same field, those published recently or in the authorized journals were selected. A total of 53 articles were included. RESULTS AND CONCLUSION: From the existing research results, positron emission tomography/magnetic resonance imaging have more advantages over traditional and other multimodality imaging techniques such as positron emission tomography/computed tomography and single-photon emission computed tomography/computed tomography, as demonstrated by the pre-clinical studies and preliminary clinical experiences, and have broader development space. So it has capacity to bring the development of molecular imaging technique and clinical diagnosis into a new area.关键词
骨关节植入物/骨与关节植入物综述/PET/MRI/多模式成像/分子影像/核医学/图像融合/图像配准/衰减校正/磁场兼容/功能影像/国家自然科学基金分类
医药卫生引用本文复制引用
张敏燕,王殊轶,严荣国,葛斌,周颖..正电子发射计算机断层显像/核磁共振：分子影像学技术新进展**★[J].中国组织工程研究,2013,(9):1687-1694,8.基金项目
国家自然科学基金青年科学基金项目(30900320)；上海市教委科研创新项目(12YZ098)。Supported by：National Natural Science Foundation for Distinguished Young Scholars, No.30900320* （30900320）
Scientific Research Innovation Project of Shanghai Commit ee of Education, No.12YZ098* （）
