中国组织工程研究Issue(23):4313-4319,7.DOI:10.3969/j.issn.2095-4344.2013.23.019
牙源和非牙源性干细胞在组织工程再生牙研究中的作用****★
Effects of dental and non-dental stem cells in the study of tissue-engineered regenerated teeth
摘要
Abstract
BACKGROUND: Absence of tooth is a common organ loss for human. Recent study of tissue-engineered organ is gradual y mature. Various adult stem cel s have been used in the study of regenerated tooth. OBJECTIVE: To summarize the properties of various adult stem cel s and to explore the effects and new progresses of various adult stem cel s in the study of regenerated teeth. METHODS: An online retrieval of PubMed database and China National Knowledge Infrastructure for articles published from 1979 to 2012 was conducted. In titles and abstracts, the keywords were “stem cel s, tooth regeneration” in English, and “stem cel s, regenerated tooth, tissue-engineered tooth, seed cel s” in Chinese. Articles addressed adult stem cel s, regenerated tooth and tooth tissue engineering. In the same field, articles published recently or in authorized journals were included. Final y, 53 articles were included. RESULTS AND CONCLUSION: Teeth grow in a special condition, and hardly regenerated. Histological engineering dental research has offered a new treatment for tooth loss treatment. A large number of experimental studies found that different adult stem cel s can have different functions in the process of regenerating teeth in vitro and in vivo, with advantages and disadvantages. In contrast, the advantage of umbilical cord blood stem cel s is more outstanding, and may play an important role in the future study of tooth regeneration.关键词
干细胞/干细胞学术探讨/根尖乳头干细胞/牙髓干细胞/牙周膜干细胞/牙囊干细胞/脱落牙乳牙牙髓干细胞/再生牙/种子细胞/综述文献/省级基金分类
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胥航,农晓琳..牙源和非牙源性干细胞在组织工程再生牙研究中的作用****★[J].中国组织工程研究,2013,(23):4313-4319,7.基金项目
广西科学基金(桂科回0836013);广西研究生教育创新计划项目(2007重16;201010598RY10;2011105981003M184)。 (桂科回0836013)