中国组织工程研究Issue(34)：6179-6182,4.DOI:10.3969/j.issn.2095-4344.2013.34.018
纳米羟基磷灰石/聚酰胺66复合生物活性椎间融合器的临床应用
Clinical application of a bioactive nano-hydroxyapatite/polyamide 66 interbody fusion cage
王茂源 1谢瑞莲 1何春耒 1刘午阳 1黄为民 1高辉1
作者信息
- 1. 赣南医学院第一附属医院骨科，江西省赣州市 341000
- 折叠
摘要
Abstract
BACKGROUND:There are various commonly used interbody fusion methods, such as autologous bone, <br> al ograft bone and titanium-based posterior lumbar interbody fusion, and each method has its own advantages and disadvantages. <br> OBJECTIVE:To observe the clinical efficacy of a bioactive nano-hydroxyapatite/polyamide 66 fusion cage in posterior lumbar interbody fusion for the treatment of lumbar disease. <br> METHODS:A retrospective case analysis was conducted on 16 cases treated with posterior lumbar interbody <br> fusion at the Department of Orthopedic, the First Affiliated Hospital of Gannan Medical University from July 2010 to December 2011, and al the patients were implanted with nano-hydroxyapatite/polyamide 66 biological activity fusion cage. <br> RESULTS AND CONCLUSION:Al the patients were fol owed-up for 10-24 months, and the lumbar pain was significant improved, the lumbar visual analogue score, lumbar Japanese Orthopaedic Association score and Oswestry disability index score were significantly improved during the final fol ow-up period (P<0.05). No internal fixation loosing or broken observed in al the patients during final fol ow-up, and al the patients obtained bone <br> fusion without nano-hydroxyapatite/polyamide 66 fusion cage displacement or subsidence. The results indicate that nano-hydroxyapatite/polyamide 66 fusion cage for the treatment of posterior lumbar interbody fusion can <br> reconstruct the lumbar stability and provide immediate stability after implantation, and has good biological activity.关键词
生物材料/纳米生物材料/骨科生物材料/纳米羟基磷灰石/聚酰胺66/椎间融合器/椎间融合/生物相容性Key words
biomaterials/nanobiomaterials/orthopedic biomaterials/nano-hydroxyapatite/polyamide 66/interbody fusion cage/interbody fusion/biocompatibility分类
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王茂源,谢瑞莲,何春耒,刘午阳,黄为民,高辉..纳米羟基磷灰石/聚酰胺66复合生物活性椎间融合器的临床应用[J].中国组织工程研究,2013,(34):6179-6182,4.
