中国组织工程研究Issue(35)：6281-6286,6.DOI:10.3969/j.issn.2095-4344.2013.35.010
兔腰椎间盘磁共振T2 mapping成像**
Magnetic resonance imaging of T2 mapping in rabbit lumbar intervertebral disc
韦文姜 1周智洋 2郭文波 1朱攀 2吴志强 1庄文权1
作者信息
- 1. 中山大学附属第一医院介入放射科，广东省广州市 510080
- 2. 中山大学附属第六医院放射科，广东省广州市 510655
- 折叠
摘要
Abstract
BACKGROUND:The magnetic resonance molecular imaging used in the research of lumbar disc degeneration includes T2 mapping and T1ρtechnologies at present. <br> OBJECTIVE:To evaluate the feasibility of 1.5 T MR equipment on T2 mapping of New Zealand white rabbits lumbar disc. <br> METHODS:T2 mapping images of New Zealand white rabbit lumbar discs were obtained on 1.5 T MR equipment. The regions of interest T2 values of lumbar discs were measured with post-processing workstation. <br> RESULTS AND CONCLUSION:Sagittal and coronal T2 maps of 3-month rabbit discs were obtained <br> satisfactorily on 1.5 T MR equipment. The regions of interest T2 values of nucleus pulposus in L 4/5 , L 5/6 and L 6/7 discs were (104.6±14.0) ms, (109.1±13.8) ms and (109.5±15.1) ms respectively at Pfirrmann <br> regions of interest T2 values of anterior annulus fibrosus in L 4/5 , L 5/6 and L 6/7 discs were (82.1±9.5) ms, (80.4± 11.2) ms and (79.9±10.6) ms respectively, and T2 values of posterior annulus fibrosus in L 4/5 , L 5/6 and L 6/7 discs were (85.8±11.9) ms, (85.1±12.1) ms and (85.3±9.3) ms respectively. There were no significant differences in T2 values of nucleus pulposus, anterior annulus fibrosus and posterior annulus fibrosus in L 4/5 , L 5/6 and L 6/7 discs at PfirrmannⅠP>g 0ra.0d5e).( However, the T2 values of nucleus pulposus were higher than those of annulus <br> fibrosus in the same discs (P<0.01), and there were no significant differences in T2 values between the anterior and posterior annulus fibrosus (P>0.05). The T2 values of rabbit lumbar discs obtained on 1.5 T MR equipment can be used for quantitative assessment of intervertebral disc signal.关键词
骨关节植入物/骨与关节图像和影像/脊柱损伤基础实验/椎间盘退变/动物模型/髓核/磁共振成像/磁共振分子影像/T2 mapping/兔/国家自然科学基金分类
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韦文姜,周智洋,郭文波,朱攀,吴志强,庄文权..兔腰椎间盘磁共振T2 mapping成像**[J].中国组织工程研究,2013,(35):6281-6286,6.
