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滑膜间充质干细胞关节腔内注射治疗关节软骨损伤

袁小龙 毕声荣 余方圆

中国组织工程研究Issue(36):5892-5897,6.
中国组织工程研究Issue(36):5892-5897,6.DOI:10.3969/j.issn.2095-4344.2015.36.027

滑膜间充质干细胞关节腔内注射治疗关节软骨损伤

Intra-articular injection of synovial mesenchymal stem cells to treat articular cartilage injury

袁小龙 1毕声荣 2余方圆3

作者信息

  • 1. 河北北方学院,河北省张家口市 075000
  • 2. 解放军第309医院关节外科,北京市 100091
  • 3. 解放军第309医院关节外科,北京市 100091
  • 折叠

摘要

Abstract

BACKGROUND:Among various seed cel s, synovial mesenchymal stem cel s have unique advantages in the repair of articular cartilage injury. OBJECTIVE:To review the progress of synovial mesenchymal stem cel s and its intra-articular injection in the treatment of articular cartilage injury. METHODS:The first author searched PubMed and CNKI by computer to retrieve articles published from January 2004 to December 2004 using the keywords of“synovial mesenchymal stem cel s;intra-articular injection;cartilage repair”in English and Chinese, respectively. Final y, 57 articles were included in result analysis. RESULTS AND CONCLUSION:It is easy to isolate and culture synovial mesenchymal stem cel s, which has great advantages in cartilage repair. What’s more, intra-articular injection therapy for articular cartilage injury is feasible and safe. Intra-articular injection of synovial mesenchymal stem cel s is a very promising treatment for cartilage damage, but there are stil many problems to be solved in the future.

关键词

干细胞/移植/滑膜间充质干细胞/注射治疗/软骨修复/国家自然科学基金

分类

医药卫生

引用本文复制引用

袁小龙,毕声荣,余方圆..滑膜间充质干细胞关节腔内注射治疗关节软骨损伤[J].中国组织工程研究,2015,(36):5892-5897,6.

基金项目

国家自然科学基金(30801159);博士后科研基金(20110491841);首都医学发展科研基金(39770714) (30801159)

中国组织工程研究

OA北大核心CSTPCD

2095-4344

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