中国组织工程研究Issue(37)：6031-6036,6.DOI:10.3969/j.issn.2095-4344.2015.37.023
延迟性肌肉酸痛与骨骼肌卫星细胞：骨骼肌损伤的修复
Delayed onset muscle soreness and muscle satellite cells:repair of skeletal muscle injury
摘要
Abstract
BACKGROUND:Skeletal muscle fiber damage that is induced by prolonged or high-intensity exercise directly cause muscle injury. OBJECTIVE:To propose the existence of a relationship between delayed onset muscle soreness and muscle satel ite cel s after skeletal muscle injury from the objective reality. METHODS:A retrieval of CNKI and PubMed databases was done for relevant literature published from February 1961 to February 2015 using the keywords of“delayed onset muscle soreness;skeletal muscle injury;satel ite cel s, skeletal muscle;myogenic regulatory factors”in Chinese and English, respectively. Final y, 59 articles were included to explore the mechanism of skeletal muscle injury accompanied by delayed onset muscle pain. RESULTS AND CONCLUSION:Skeletal muscle micro-injury mainly refers to ultrastructural destroy and metabolic disorders, involving muscle cel membrane, cytoskeleton, sarcomere and mitochondria, thereby leading to skeletal muscle contraction dysfunction that is often accompanied with delayed onset muscle soreness. Eccentric exercise can cause the severest microdamage to the skeletal muscle fibers. The occurrence of delayed onset muscle soreness can stimulate the secretion of growth factors from skeletal muscle satel ite cel s to a certain extent, and the time series of delayed onset muscle soreness triggered by sustained high-intensity eccentric exercise has a certain correlation with the time series of the proliferation of skeletal muscle satel ite cel s.关键词
组织构建/组织工程/延迟性肌肉酸痛/骨骼肌损伤/骨骼肌卫星细胞/调节因子分类
医药卫生引用本文复制引用
张翔,柴志铭,赵丽..延迟性肌肉酸痛与骨骼肌卫星细胞：骨骼肌损伤的修复[J].中国组织工程研究,2015,(37):6031-6036,6.基金项目
忻州师范学院重点建设学科项目(xk201403) （xk201403）
