中国组织工程研究Issue(42)：6740-6745,6.DOI:10.3969/j.issn.2095-4344.2015.42.004
失下牙槽神经支配与拔牙窝新骨形成及骨量保持
Denervation of the inferior alveolar nerve is associated with bone formation and bone mass maintenance in extraction sockets
摘要
Abstract
BACKGROUND: There is a close relationship between innervations and bone formation and bone mass maintenance in the extraction sockets. OBJECTIVE:To study the possible effect of denervations on the regulation of new bone formation and bone mass maintenance in the extraction sockets. METHODS:The unilateral inferior nerve of dogs was sectioned to establish an animal denervation model. The normal side was used as control. After model establishment, the premolars of denervated side and normal side were extracted. Histological method was used to test new bone formation and bone mass maintenance in the extraction sockets at the 2nd, 4th, 8th and 12th weeks after tooth extraction. RESULTS AND CONCLUSION:The percentage of new bone areas in the extraction sockets was significantly lower in the experiment group than the control group at weeks 2, 4, 8 after tooth extraction (P < 0.01). The height difference between the buccal and lingual alveolar ridge was higher in the experimental group than the control group at weeks 2, 4, 8, 12 after tooth extraction (P < 0.05 or P < 0.01). These findings indicate that denervation is closely related with new bone formation and bone mass maintenance in the extraction sockets.关键词
组织构建/骨组织工程/神经支配/失神经支配/拔牙窝/骨愈合/骨量/国家自然科学基金分类
医药卫生引用本文复制引用
王承勇,陈伟辉,卢萌,王锦,茅传青,林海..失下牙槽神经支配与拔牙窝新骨形成及骨量保持[J].中国组织工程研究,2015,(42):6740-6745,6.基金项目
国家自然科学基金(31070838)；福建省自然科学基金杰出青年项目(2012J06017)；福建省卫生厅青年基金(2012-1-20)Funding:the National Natural Science Foundation of China, No.31070838 （31070838）
the Natural Science Foundation of Fujian Province, No.2012J06017 （）
the Youth Fund of Fujian Provincial Health Department, No.2012-1-20 （）
