现代医药卫生Issue(21)：3222-3224,3.DOI:10.3969/j.issn.1009-5519.2015.21.006
ICU患者尿路感染的病原菌分布及耐药性分析
Distribution of pathogenic bacteria and analysis of drug re sistance in ICU patients with urinary tract infection
张间霞 1吴英 1陈家钖 1肖海艳 1雷蕾 1陈胜男1
作者信息
摘要
Abstract
Objective To investigate the distribution and drug resistance of common pathogenic bacteria in ICU patients with urinary tract infection so as to provide the basis for rationally selecting the antibacterial drugs in clinic and guiding the clini-cally rational drug use. Methods 225 strains of pathogenic bacteria isolated from the urine samples among ICU patient with uri-nary tract infection in our hospital from January 1, 2013 to December 31,2014 were performed the identification and drug suscep-tibility test. Results Among 225 strains of pathogenic bacteria,119 strains(52.9%) were Gram-negative bacteria,35 strains (15.6%)were Gram-positive bacteria,53 strains(23.6%) were fungi and 18 strains(8.0%) were other bacteria. Gram-positive bacte-ria were sensitive to both vancomycin(VA) and linezolid(LZD),Gram-negative bacteria were sensitive to both imipenem(IPM) and meropenem(MEM),and fungi were sensitive to amphotericin B(AMPHO) and nystatin(NYST). In ESBLs producing bacteria, Escherichia coli was predominant,its detection rate was 47.7%(21/44). Conclusion Gram-negative bacteria are the major pathogens in urinary tract infection and their resistance to commonly used antibacterial drugs shows the upward trend ,which has important significance to guide rational use of antibacterial drugs in clinic and select effective antibacterial drugs.关键词
重症监护病房/革兰氏阴性菌/革兰氏阳性菌/真菌/泌尿道感染/药物耐受性/抗菌药/微生物敏感性试验Key words
Intensive care units/Gram-negative bacteria/Gram-positive bacteria/Fungi/Urinary tract infec-tions/Drug tolerance/Anti-bacterial agents/Microbial sensitivity tests引用本文复制引用
张间霞,吴英,陈家钖,肖海艳,雷蕾,陈胜男..ICU患者尿路感染的病原菌分布及耐药性分析[J].现代医药卫生,2015,(21):3222-3224,3.
