刑事技术Issue(5)：376-378,3.DOI:10.16467/j.1008-3650.2015.05.007
不完整STR分型的价值挖掘
The Potential Value of Forensic Partial DNA Profiles
陈静 1苑美青 1谢群 1徐秀兰 1徐珍 1李万水1
作者信息
- 1. 公安部物证鉴定中心 法医遗传学公安部重点实验室，北京 100038
- 折叠
摘要
Abstract
Complete and clear DNA profiles are the decisive evidence for criminal suspects to be identified. Whereas, in forensic practice, DNA profiles come out at times as mixed or partial ones, resulting in the relevant cases turning into “cold cases” because of chronic postponement out of inability to compare and match. The Express Search of National Database can offer crucial support for solving this sort of cases if the relevant partial DNA spectrums from one “cold case” become available. Based on this idea, 21 unsolved cases in the year of 2011 were assorted in combination of National Database by the mixed DNA profiles being de-convolved into individual spectrums to make the potential suspects’ able to be matched. This handling conduced 19 cases having got their valuable DNA spectrums, successfully directing two murder cases to be solved by the above method of de-convolution. How to produce an available DNA profile and split out its usable spectrums is the key to solve the cases of mixed evidential materials without suspects attached. Consequently, the optimization of amplification parameters and conditions, selection of reliable loci to be matched and ascertainment of multiple chosen collocations were analyzed and discussed in this paper, therefore putting forth the essentially technical points on de-convolving a mixed DNA profile. This paper presents the deep mining of partial DNA profiles to exert their potential values with National Database to play its predominance of data and information, bringing the dormant partial DNA spectrums into life and “cold cases”uncovered, very beneficial to supply thoughts and reference for setting up new patterns of cases solving.关键词
法医遗传学/不完整STR分型/混合分型/拆分/数据库检索Key words
forensic genetics/partial STR profile/mixed DNA profile/de-convolution/database search分类
社会科学引用本文复制引用
陈静,苑美青,谢群,徐秀兰,徐珍,李万水..不完整STR分型的价值挖掘[J].刑事技术,2015,(5):376-378,3.
