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基于层状二硫化钼-石墨烯构建新型17β-雌二醇电化学生物传感器

骆定法 刘雪

信阳师范学院学报(自然科学版)Issue(4):542-545,4.
信阳师范学院学报(自然科学版)Issue(4):542-545,4.DOI:10.3969/j.issn.1003-0972.2015.04.019

基于层状二硫化钼-石墨烯构建新型17β-雌二醇电化学生物传感器

A Novel Electrochemical Bioensor for 17β-estradiol Based on MoS2-Graphene Nanocomposite

骆定法 1刘雪1

作者信息

  • 1. 信阳师范学院 化学化工学院,河南 信阳 464000
  • 折叠

摘要

Abstract

MoS2‐graphene nanocomposite was prepared .A novel electrochemical biosensor was constructed by immobilizing of aptamer on the electrode that was modified with Au nanoparticles and MoS2‐graphene .The electrochemical behavior of the modified electrode was tested by cyclic voltammograms ,differential pulse volta‐mmetric and electrochemical impedance .The reaction time and temperature between 17β‐estradiol and aptamer were optimized .The experimental results showed that the proposed assay exhibited a good linear relationship between the peak current and the concentration of 17β‐estradiol in the range of 1 .0 × 10 - 11 ~ 1 .0 × 10 - 8 mol/L with the detection limit of 5 .0 × 10 - 12 mol/L .The biosensor had good selectivity and stability .

关键词

二硫化钼-石墨烯纳米复合材料/17β-雌二醇/适配体/电化学生物传感器

Key words

MoS2-graphene nanocomposite/17β-estradiol/aptamer/electrochemical biosensor

分类

化学化工

引用本文复制引用

骆定法,刘雪..基于层状二硫化钼-石墨烯构建新型17β-雌二醇电化学生物传感器[J].信阳师范学院学报(自然科学版),2015,(4):542-545,4.

基金项目

河南省科技计划项目 ()

信阳师范学院学报(自然科学版)

OA北大核心CSTPCD

1003-0972

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