新医学Issue(10)：653-656,4.DOI:10.3969/g.issn.0253-9802.2015.10.003
妊娠期抗病毒治疗阻断 HBV 母婴传播的研究进展
Research progress of blocking mother-to-infant transmission of hepatitis B virus through antiviral ther-apy during pregnancy
曾映夫 1林潮双1
作者信息
- 1. 510630 广州，中山大学附属第三医院感染性疾病科
- 折叠
摘要
Abstract
Hepatitis B virus (HBV)infection is a global health problem with approximately 400 mil-lion carriers across the world.In China,nearly 1 20 million individuals are HBsAg positive.Over 50% of these carriers are infected vertically from their mothers,and vertically-acquired HBV infection is highly likely to be-come chronic.Previous studies have demonstrated that high viral load in pregnant woman is the most important risk factor of mother-to-infant transmission,which is also correlated with positive HBeAg.Administration of an-tiviral drugs during pregnancy can minimize the viral load before delivery remarkably reduce the risk of mother-to-infant transmission of HBV.After fully considering the advantages and disadvantages of antiviral agents to mother and fetus,antiviral therapy may be considered to the pregnant women during the late trimester.关键词
乙型肝炎病毒/妊娠/母婴传播/抗病毒治疗Key words
Hepatitis B virus/Pregnancy/Mother-to-infant transmission/Antiviral therapy引用本文复制引用
曾映夫,林潮双..妊娠期抗病毒治疗阻断 HBV 母婴传播的研究进展[J].新医学,2015,(10):653-656,4.
