临床医学工程Issue(10)：1313-1314,2.DOI:10.3969/j.issn.1674-4659.2015.10.1313
阿莫西林和呋喃唑酮为基础的四联、三联疗法根除幽门螺杆菌的临床疗效观察
Clinical Effect Observation of Quadruple Therapy and Triple Therapy Based on Amoxicillin and Furazolidone for ;Eradication of Helicobacter Pylori
董辉1
作者信息
- 1. 广东省化州市人民医院急诊科，广东化州525100
- 折叠
摘要
Abstract
Objective To analyze and compare the clinical effects of quadruple therapy and triple therapy based on amoxicillin and furazolidone for eradication of Helicobacter pylori (Hp). Methods 440 patients with gastrosis resulted by Hp were randomly divided into four groups, with 110 cases in each group. The quadruple group (contained PPI) was treated with proton pump inhibitor (PPI) +bismuth potassium citrate+amoxicillin+furazolidone;the triple group (contained RBC) was treated with ranitidine bismuth citron acid (RBC) +amoxicillin+furazolidone;the triple group (contained PPI) was treated with PPI+amoxicillin+furazolidone;the triple group (contained bismuth and potassium) was treated with bismuth potassium citrate + amoxicillin + furazolidone. The clinical effects and incidence of adverse reactions were compared between four groups. Results The eradication rate of Hp in quadruple group (contained PPI) was significantly higher than that in triple group (contained RBC), triple group (contained PPI) and triple group (contained bismuth and potassium);the incidence of adverse reactions in quadruple group (contained PPI) was significantly lower than that in other three groups;all the difference was statistical (P <0.05). Conclusions Quadruple therapy (contained PPI) has high Hp eradication rate, without serious adverse reactions, which also has better anti-drug resistance and deserves promotion and application.关键词
阿莫西林/呋喃唑酮/幽门螺杆菌/质子泵抑制剂/枸椽酸铋钾Key words
Amoxicillin/Furazolidone/Helicobacter pylori/Proton pump inhibitor/Bismuth potassium citrate分类
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董辉..阿莫西林和呋喃唑酮为基础的四联、三联疗法根除幽门螺杆菌的临床疗效观察[J].临床医学工程,2015,(10):1313-1314,2.
