临床医学工程Issue(10):1367-1368,2.DOI:10.3969/j.issn.1674-4659.2015.10.1367
羊水胎粪污染程度和持续时间与胎盘病理改变的关系
Relationship Between the Degree and Duration of Meconium-stained Amniotic Fluid and Pathological Changes of the ;Placenta
陈丽芬 1耿春惠 1张丽燕1
作者信息
- 1. 暨南大学医学院附属宝安妇幼保健院,广东深圳518133
- 折叠
摘要
Abstract
Objective To investigate the relationship between the degree and duration of meconium-stained amniotic fluid (MSAF) and pathological changes of the placenta. Methods The pathological findings of 356 pregnant woman with MSAF were retrospectively analyzed, and the incidence of placenta pathological changes in different degree of MSAF (including degreeⅠ,Ⅱ,Ⅲ) was observed, the difference of pathological changes rate and type was compared in the long duration and short duration MSAF group. Results The incidence of placenta pathological changes in degreeⅠ, Ⅱ and Ⅲ MSAF groups were 38.2%, 49.5% and 72.0% respectively, the difference was statistical (P<0.01). The incidence of placenta pathological changes in long duration MSAF group was significantly higher than that in short duration MSAF group, the incidence of chorioamnionitis in long duration MSAF group was significantly lower than that in short duration MSAF group, the incidence of villus interstitial fibrosis and syncytiotrophoblast proliferation were significantly higher than that in short duration MSAF group, all the difference was statistical (P<0.05). Conclusions The degree and duration of MSAF have positive correlation with pathological changes of the placenta. The most common type of pathological changes in short duration MSAF is acute inflammatory exudation, and the common type of pathological changes in long duration MSAF are chronic inflammation, villus interstitial fibrosis and syncytiotrophoblast proliferation.关键词
羊水胎粪污染/胎盘/病理变化Key words
Meconium-stained amniotic fluid/Placenta/Pathological change分类
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陈丽芬,耿春惠,张丽燕..羊水胎粪污染程度和持续时间与胎盘病理改变的关系[J].临床医学工程,2015,(10):1367-1368,2.