临床医学工程2015，Vol.22Issue(11)：1420-1421,2.DOI:10.3969/j.issn.1674-4659.2015.11.1420
血清CRP、IL-6、PCT检测在新生儿败血症诊治中的价值
Value of Detection of Serum CRP, IL-6 and PCT in the Diagnosis and Treatment of Neonatal Sepsis
吕晓丹 1刘巧红 1张莉1
作者信息
- 1. 深圳市龙岗区妇幼保健院, 广东深圳 518000
- 折叠
摘要
Abstract
Objective To explore the clinical value and significance of combined detection of serum C-reactive protein (CRP), interleukin-6 (IL-6), and procalcitonin (PCT) in the diagnosis and treatment of neonatal sepsis. Methods 100 cases of newborns with sepsis in Neonatology Departmen of our hospital from February 2012 to February 2015 were selected as observation group, and 100 cases without sepsis in Neonatology Departmen of our hospitat at the same time were selected as control group. The levels of serum CRP, IL-6 and PCT of the two groups were detected and analyzed. Results The levels of serum CRP, IL-6 and PCT of the observation group were significantly higher than those of the control group (P<0.05). The sensitivity, positive predictive value and negative predictive value of combined detection of three indicators were significantly higher than those of detection of single indicator (P<0.05). The levels of serum CRP, IL-6 and PCT of neonatal sepsis were positively associated with sequential organ failure assessment (SOFA), and negatively associated with pediatric critical illness score (PCIS). Conclusions For newborns with suspected sepsis, the detection of serum of CRP, IL-6 and PCT is conducive to early diagnosis and disease condition assessment, so as to reduce the incidence of adverse events, which is worthy of clinical application.关键词
新生儿败血症/C反应蛋白/白介素-6/降钙素原/意义Key words
Neonatal sepsis/C-reactive protein (CRP)/Interleukin-6 (IL-6)/Procalcitonin (PCT)/Significance分类
医药卫生引用本文复制引用
吕晓丹,刘巧红,张莉..血清CRP、IL-6、PCT检测在新生儿败血症诊治中的价值[J].临床医学工程,2015,22(11):1420-1421,2.
