临床医学工程2015，Vol.22Issue(11)：1434-1435,2.DOI:10.3969/j.issn.1674-4659.2015.11.1434
PTEN表达对妊娠期糖尿病患者的临床意义研究
Clinical Significance of PTEN Expression in Patients with Gestational Diabetes Mellitus
摘要
Abstract
Objective To explore the significance of PTEN expression in patients with gestational diabetes mellitus. Methods 60 patients who suffered from the gestational diabetes mellitus were selected and divided into good blood glucose control group and poor blood glucose control group, with 30 patients in each group. 30 normal pregnant women in our hospital at the same period were selected as normal group. The expression levels of PTEN in placenta tissues of 3 groups were detected by immunohistochemistry. Results The expression of PTEN was in placental vascular endothelial cells, while villous stromal cells and syncytiotrophoblast had almost no PTEN positive reaction. The expression of PTEN in the poor blood glucose control group, good blood glucose control group and normal group increased in turn, with statistically significant difference (P<0.05). Conclusions PTEN is decreasingly expressed in gestational diabetes mellitus, which may play a role in the pathological process of gestational diabetes mellitus.关键词
PTEN/妊娠期糖尿病/胎盘组织Key words
PTEN/Gestational diabetes mellitus/Placenta分类
医药卫生引用本文复制引用
申舒静..PTEN表达对妊娠期糖尿病患者的临床意义研究[J].临床医学工程,2015,22(11):1434-1435,2.基金项目
深圳市科技计划项目 "妊娠期糖尿病患者胎盘组织中PTEN的表达及意义" (项目编号: 201507034) （项目编号: 201507034）
