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周剂量奈达铂同步放化疗治疗中晚期宫颈癌的临床研究

陈静 陆谔梅 黄建

医学信息Issue(18):57-57,58,2.
医学信息Issue(18):57-57,58,2.

周剂量奈达铂同步放化疗治疗中晚期宫颈癌的临床研究

Clinical study on weekly nadaplatin concurrent chemoradiotherapy for local advanced cervical cancer

陈静 1陆谔梅 1黄建1

作者信息

  • 1. 南京医科大学附属江苏省肿瘤医院妇放科,江苏 南京 210009
  • 折叠

摘要

Abstract

Objective To analyze the clinical ef ect and toxicity of nadaplatin concurrent chemoradiotherapy for local y advanced cervical cancer. Methods Fifty patients with local advanced cervical cancer were randomly divided into nadaplatin concurrent chemo-radiotherapy group ( 25 cases) and only radiotherapy group ( 25 cases) . The survival rates toxicity of the two groups were compared. Results The total ef ective rates were 92.0% and 80.0%, 2-year survival rates were 76.0% and 56.0%, recurrence and metastasis rates were 16.0% and 44.0% in nadaplatin concurrent chemo-radiotherapy group and only radiotherapy group respectively with significant dif erence(P<0.05).But the incidence of bone marrow inhibition and gastrointestinal reaction in nadaplatin concurrent chemo-radiotherapy group were higher than that in only radiotherapy group. Conclusion Compared with only radiotherapy group,the total ef ective rates and survival rates were higher in nadaplatin concurrent chemo-radiotherapy group,but bone marrow inhibition and gastrointestinal reaction were severer for local advanced cervical cancer.

关键词

同步放化疗/宫颈癌/疗效/毒副作用

Key words

Concurrent Chemoradiotherapy/Cervical Cancer/Clinical Ef ect/Toxicity

引用本文复制引用

陈静,陆谔梅,黄建..周剂量奈达铂同步放化疗治疗中晚期宫颈癌的临床研究[J].医学信息,2013,(18):57-57,58,2.

医学信息

1006-1959

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