摘要
Abstract
Objective To study the expressions and significance of heat shock protein 27 (Hsp27) in brain tissue fol owing transient cerebral ischemic reperfusion in gerbils. Methods A cerebral ischemia-reperfusion model in gerbils was established by clamping both common carotids.The expressions of Hsp27 in brain tissue were detected by using immunohistochemistry technique in normal control group, sham operation group, ischemia-reperfusion (IR) group. Results Compared to that of normal control group, the expressions of Hsp27 in neurons gliacytes of ischemia-reperfusion gerbils were evidently increased at the 6th hour,1st day, 3rd day and 7th day,especial y at the 3rd day﹙p﹤0.05﹚. Conclusion The expressions of Hsp27 in neurons and gliacytes of gerbils were evidently increased fol owing cerebral ischemia-reperfusion.,which maybe a protective reaction to injury.关键词
脑缺血再灌注/Hsp27/沙鼠Key words
Cerebral ischemia-reperfusion/Hsp27/Gerbils
